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D, MS, RA, AS, SLE, psoriasis, and psoriatic arthritis.GUT MICROBIOME: AN OVERVIEW IMMUNE-MEDIATED INFLAMMATORY DISEASE COMORBIDITYImmune-mediated inflammatory disease are defined by the principle organ system that is affected [the gastrointestinal tract in IBD, the synovium in RA and the central nervous system (CNS) in MS]; however, they are associated with comorbidities that extend beyond the pr