Cantly increased in the DKO rd8 retina compared to the control, C57Bl/6N rd8 retina (Figure 3A). IL-1 expression was not significantly changed (Figure 3B). ABCG1 and ABCA1 expression was significantly downregulated in the DKO rd8 retina (Figure 3C,D, respectively), a phenomenon consistent with increased cholesterol accumulation and therefore inflammation in DKO rd8 eyes. OTC suppresses pro-inflamm